The microbiologic safety of umbilical cord blood transfusion for children with severe anemia in Mombasa, Kenya
Identifieur interne : 000758 ( Main/Exploration ); précédent : 000757; suivant : 000759The microbiologic safety of umbilical cord blood transfusion for children with severe anemia in Mombasa, Kenya
Auteurs : Oliver W. Hassall [Royaume-Uni] ; Johnstone Thitiri [Royaume-Uni] ; Greg Fegan [Royaume-Uni] ; Lewa Pole [Royaume-Uni] ; Salim Mwarumba [Royaume-Uni] ; Douglas Denje [Royaume-Uni] ; Kongo Wambua [Royaume-Uni] ; Brett Lowe [Royaume-Uni] ; Christopher M. Parry [Royaume-Uni] ; Kishor Mandaliya [Royaume-Uni] ; Kathryn Maitland [Royaume-Uni] ; Imelda Bates [Royaume-Uni]Source :
- Transfusion [ 0041-1132 ] ; 2012-07.
Descripteurs français
- Wicri :
- geographic : Kenya.
- topic : Transfusion sanguine, Don.
English descriptors
- KwdEn :
- Antenatal, Bacillus, Bacterial contamination, Blood donors, Blood packs, Blood safety, Blood transfusion, Clinical trials, Contaminant, Contamination, Conventional blood, Conventional blood donors, Conventional blood pack, Conventional blood packs, Conventional donors, Cord, Cord blood, Cord blood collection, Cord blood donation, Cord blood donations, Cord blood donors, Cord blood pack, Cord blood packs, Cord blood transfusion, Cpgh, Donation, Donor, General hospital, Hassall, July, Kenya, Kenyan hospital, Labor ward, Maternal serum, Mombasa, Positive poststorage culture, Poststorage, Poststorage culture, Poststorage cultures, Primary objective, Rbtc, Residual risk, Screening, Screening culture, Screening cultures, Serology results, Seroreactivity, Severe anaemia, Severe anemia, Staphylococcus epidermidis, Streptococcus, Streptococcus group, Subsaharan africa, Syphilis, Transfusion, Transfusion volume, Umbilical, West africa, Whole blood, Young children.
- Teeft :
- Antenatal, Bacillus, Bacterial contamination, Blood donors, Blood packs, Blood safety, Blood transfusion, Clinical trials, Contaminant, Contamination, Conventional blood, Conventional blood donors, Conventional blood pack, Conventional blood packs, Conventional donors, Cord, Cord blood, Cord blood collection, Cord blood donation, Cord blood donations, Cord blood donors, Cord blood pack, Cord blood packs, Cord blood transfusion, Cpgh, Donation, Donor, General hospital, Hassall, July, Kenya, Kenyan hospital, Labor ward, Maternal serum, Mombasa, Positive poststorage culture, Poststorage, Poststorage culture, Poststorage cultures, Primary objective, Rbtc, Residual risk, Screening, Screening culture, Screening cultures, Serology results, Seroreactivity, Severe anaemia, Severe anemia, Staphylococcus epidermidis, Streptococcus, Streptococcus group, Subsaharan africa, Syphilis, Transfusion, Transfusion volume, Umbilical, West africa, Whole blood, Young children.
Abstract
BACKGROUND: Severe anemia requiring blood transfusion is common in hospitalized young children in sub‐Saharan Africa but blood is often in short supply. Umbilical cord blood may be a useful source of blood if microbiologic safety concerns can be addressed.
Url:
DOI: 10.1111/j.1537-2995.2011.03487.x
Affiliations:
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Hassall</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation><affiliation></affiliation></author><author><name sortKey="Thitiri, Johnstone" sort="Thitiri, Johnstone" uniqKey="Thitiri J" first="Johnstone" last="Thitiri">Johnstone Thitiri</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Fegan, Greg" sort="Fegan, Greg" uniqKey="Fegan G" first="Greg" last="Fegan">Greg Fegan</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Pole, Lewa" sort="Pole, Lewa" uniqKey="Pole L" first="Lewa" last="Pole">Lewa Pole</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Mwarumba, Salim" sort="Mwarumba, Salim" uniqKey="Mwarumba S" first="Salim" last="Mwarumba">Salim Mwarumba</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Denje, Douglas" sort="Denje, Douglas" uniqKey="Denje D" first="Douglas" last="Denje">Douglas Denje</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Wambua, Kongo" sort="Wambua, Kongo" uniqKey="Wambua K" first="Kongo" last="Wambua">Kongo Wambua</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Lowe, Brett" sort="Lowe, Brett" uniqKey="Lowe B" first="Brett" last="Lowe">Brett Lowe</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Parry, Christopher M" sort="Parry, Christopher M" uniqKey="Parry C" first="Christopher M." last="Parry">Christopher M. Parry</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Mandaliya, Kishor" sort="Mandaliya, Kishor" uniqKey="Mandaliya K" first="Kishor" last="Mandaliya">Kishor Mandaliya</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Maitland, Kathryn" sort="Maitland, Kathryn" uniqKey="Maitland K" first="Kathryn" last="Maitland">Kathryn Maitland</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author><author><name sortKey="Bates, Imelda" sort="Bates, Imelda" uniqKey="Bates I" first="Imelda" last="Bates">Imelda Bates</name><affiliation wicri:level="4"><country xml:lang="fr" wicri:curation="lc">Royaume-Uni</country><wicri:regionArea>From the Centre for Geographic Medicine Research (Coast), Kenya Medical Research Institute/Wellcome Trust Research Programme, Kilifi, Kenya; the Department of Primary Health Care and the Centre for Clinical Vaccinology & Tropical Medicine, University of Oxford, Oxford, UK; the Coast Provincial General Hospital and the Regional Blood Transfusion Centre, Mombasa, Kenya; Angkor Hospital for Children, Mahidol‐Oxford Tropical Medicine Research Unit, Siem Reap, Cambodia; the Department of Paediatrics, Imperial College London, London, UK; and the Liverpool School of Tropical Medicine, Liverpool</wicri:regionArea><orgName type="university">Université d'Oxford</orgName><placeName><settlement type="city">Oxford</settlement><region type="nation">Angleterre</region><region type="région" nuts="1">Oxfordshire</region></placeName></affiliation></author></analytic><monogr></monogr><series><title level="j" type="main">Transfusion</title><title level="j" type="alt">TRANSFUSION</title><idno type="ISSN">0041-1132</idno><idno type="eISSN">1537-2995</idno><imprint><biblScope unit="vol">52</biblScope><biblScope unit="issue">7</biblScope><biblScope unit="page" from="1542">1542</biblScope><biblScope unit="page" to="1551">1551</biblScope><biblScope unit="page-count">10</biblScope><publisher>Blackwell Publishing Inc</publisher><pubPlace>Malden, USA</pubPlace><date type="published" when="2012-07">2012-07</date></imprint><idno type="ISSN">0041-1132</idno></series></biblStruct></sourceDesc><seriesStmt><idno type="ISSN">0041-1132</idno></seriesStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Antenatal</term><term>Bacillus</term><term>Bacterial contamination</term><term>Blood donors</term><term>Blood packs</term><term>Blood safety</term><term>Blood transfusion</term><term>Clinical trials</term><term>Contaminant</term><term>Contamination</term><term>Conventional blood</term><term>Conventional blood donors</term><term>Conventional blood pack</term><term>Conventional blood packs</term><term>Conventional donors</term><term>Cord</term><term>Cord blood</term><term>Cord blood collection</term><term>Cord blood donation</term><term>Cord blood donations</term><term>Cord blood donors</term><term>Cord blood pack</term><term>Cord blood packs</term><term>Cord blood transfusion</term><term>Cpgh</term><term>Donation</term><term>Donor</term><term>General hospital</term><term>Hassall</term><term>July</term><term>Kenya</term><term>Kenyan hospital</term><term>Labor ward</term><term>Maternal serum</term><term>Mombasa</term><term>Positive poststorage culture</term><term>Poststorage</term><term>Poststorage culture</term><term>Poststorage cultures</term><term>Primary objective</term><term>Rbtc</term><term>Residual risk</term><term>Screening</term><term>Screening culture</term><term>Screening cultures</term><term>Serology results</term><term>Seroreactivity</term><term>Severe anaemia</term><term>Severe anemia</term><term>Staphylococcus epidermidis</term><term>Streptococcus</term><term>Streptococcus group</term><term>Subsaharan africa</term><term>Syphilis</term><term>Transfusion</term><term>Transfusion volume</term><term>Umbilical</term><term>West africa</term><term>Whole blood</term><term>Young children</term></keywords><keywords scheme="Teeft" xml:lang="en"><term>Antenatal</term><term>Bacillus</term><term>Bacterial contamination</term><term>Blood donors</term><term>Blood packs</term><term>Blood safety</term><term>Blood transfusion</term><term>Clinical trials</term><term>Contaminant</term><term>Contamination</term><term>Conventional blood</term><term>Conventional blood donors</term><term>Conventional blood pack</term><term>Conventional blood packs</term><term>Conventional donors</term><term>Cord</term><term>Cord blood</term><term>Cord blood collection</term><term>Cord blood donation</term><term>Cord blood donations</term><term>Cord blood donors</term><term>Cord blood pack</term><term>Cord blood packs</term><term>Cord blood transfusion</term><term>Cpgh</term><term>Donation</term><term>Donor</term><term>General hospital</term><term>Hassall</term><term>July</term><term>Kenya</term><term>Kenyan hospital</term><term>Labor ward</term><term>Maternal serum</term><term>Mombasa</term><term>Positive poststorage culture</term><term>Poststorage</term><term>Poststorage culture</term><term>Poststorage cultures</term><term>Primary objective</term><term>Rbtc</term><term>Residual risk</term><term>Screening</term><term>Screening culture</term><term>Screening cultures</term><term>Serology results</term><term>Seroreactivity</term><term>Severe anaemia</term><term>Severe anemia</term><term>Staphylococcus epidermidis</term><term>Streptococcus</term><term>Streptococcus group</term><term>Subsaharan africa</term><term>Syphilis</term><term>Transfusion</term><term>Transfusion volume</term><term>Umbilical</term><term>West africa</term><term>Whole blood</term><term>Young children</term></keywords><keywords scheme="Wicri" type="geographic" xml:lang="fr"><term>Kenya</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Transfusion sanguine</term><term>Don</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract">BACKGROUND: Severe anemia requiring blood transfusion is common in hospitalized young children in sub‐Saharan Africa but blood is often in short supply. Umbilical cord blood may be a useful source of blood if microbiologic safety concerns can be addressed.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country><region><li>Angleterre</li><li>Oxfordshire</li></region><settlement><li>Oxford</li></settlement><orgName><li>Université d'Oxford</li></orgName></list><tree><country name="Royaume-Uni"><region name="Angleterre"><name sortKey="Hassall, Oliver W" sort="Hassall, Oliver W" uniqKey="Hassall O" first="Oliver W." last="Hassall">Oliver W. Hassall</name></region><name sortKey="Bates, Imelda" sort="Bates, Imelda" uniqKey="Bates I" first="Imelda" last="Bates">Imelda Bates</name><name sortKey="Denje, Douglas" sort="Denje, Douglas" uniqKey="Denje D" first="Douglas" last="Denje">Douglas Denje</name><name sortKey="Fegan, Greg" sort="Fegan, Greg" uniqKey="Fegan G" first="Greg" last="Fegan">Greg Fegan</name><name sortKey="Lowe, Brett" sort="Lowe, Brett" uniqKey="Lowe B" first="Brett" last="Lowe">Brett Lowe</name><name sortKey="Maitland, Kathryn" sort="Maitland, Kathryn" uniqKey="Maitland K" first="Kathryn" last="Maitland">Kathryn Maitland</name><name sortKey="Mandaliya, Kishor" sort="Mandaliya, Kishor" uniqKey="Mandaliya K" first="Kishor" last="Mandaliya">Kishor Mandaliya</name><name sortKey="Mwarumba, Salim" sort="Mwarumba, Salim" uniqKey="Mwarumba S" first="Salim" last="Mwarumba">Salim Mwarumba</name><name sortKey="Parry, Christopher M" sort="Parry, Christopher M" uniqKey="Parry C" first="Christopher M." last="Parry">Christopher M. Parry</name><name sortKey="Pole, Lewa" sort="Pole, Lewa" uniqKey="Pole L" first="Lewa" last="Pole">Lewa Pole</name><name sortKey="Thitiri, Johnstone" sort="Thitiri, Johnstone" uniqKey="Thitiri J" first="Johnstone" last="Thitiri">Johnstone Thitiri</name><name sortKey="Wambua, Kongo" sort="Wambua, Kongo" uniqKey="Wambua K" first="Kongo" last="Wambua">Kongo Wambua</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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